Terbutaline Sulphate Tablets

Therapeutic Indication

Asthma (acute and chronic management)

Relief of reversible bronchospasm

Chronic Obstructive Pulmonary Disease (COPD)

Exercise-induced bronchospasm

Occasional use in preterm labor (uterine relaxant)

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Terbutaline

Tablet

Terbutaline Sulphate is a beta-2 adrenergic agonist bronchodilator used for the treatment of asthma, bronchospasm, and chronic obstructive pulmonary disease (COPD). It relaxes airway smooth muscles, improving airflow and breathing.

Speciality	Pulmonology \| Emergency Medicine \| Obstetrics
Tags	Bronchodilator \| Asthma Relief \| COPD Management \| β2-Agonist \| Respiratory Therapy
Strength	2.5 mg 5 mg
Packing Size	10 Tablets

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Mechanism

Terbutaline selectively stimulates beta-2 adrenergic receptors in bronchial smooth muscle, leading to relaxation of airways, bronchodilation, and relief of bronchospasm.

Pharmacokinetics

Absorption: Rapidly absorbed orally; peak plasma levels in 2–3 hrs.
Distribution: Widely distributed; low protein binding (~20%).
Metabolism: Partially metabolized in liver via conjugation.
Excretion: Primarily renal excretion, unchanged drug and metabolites.
Half-life: ~3–4 hrs.

Side Effects

Tremors
Palpitations
Nervousness
Headache
Rare: Hypokalemia, arrhythmias

Contraindication

Hypersensitivity to Terbutaline
Severe cardiac disease
Use cautiously in hyperthyroidism

Interaction

Beta-blockers antagonize bronchodilator effect
Other sympathomimetics increase cardiovascular risk
Diuretics may enhance hypokalemia

Warning and Precautions

Do not exceed recommended dose
Monitor cardiac function in patients with heart disease
Use cautiously in pregnancy

Dosage

As directed by the Physician.

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Terbutaline Tablets